'Splenda side effects' gets about a quarter Million hits!
Perfect illustration of, all that Information: so little you can trust.
I have no idea (that I'd ~trust ;-) which of the extant choices are least noxious *for Me*, but adding 'for diabetics' - only cuts the hits to 165K (!) Presumably it is individual metabolism, genetics which would determine a tolerance for the negatives; pity we don't even know our own 'tolerances', I wot.
My WAG is that, because of the consequences of n! .. much of the 'data' wouldn't pass Stat 101; all one can hope for, I guess - is to stumble upon a researcher with a semblance of non-trivial data and enough corroboration (not 10 folks quoting each other!) Circle game.
I tried some ice cream w/Splenda. Seemed better tasting than Nutrasweet? which I probably had <10 times. Quite less of that aftertaste I can't accept - of prevous Diet-whatevers. But I did notice an ""odd"" after-effect.. sorta bloated? or vaguely unsettled-in-stomach; ie just as 'vague' an experience as these words!
Luck balancing the Unknowns,
Ashton