It >does< taste good. I've had the Breyer's ice cream sweetened with sucralose, and it's very good. I haven't noticed any side effects, but I have not been looking for anything, either. When I was first diagnosed with diabetes ~1 year ago, the lady at the ADA education I went to suggested the use of Splenda, and the ADA's website recommends it as well on their [link|http://www.diabetes.org/nutrition-and-recipes/nutrition/sweeteners.jsp|sweeteners] page stating:
Low Calorie Sweeteners
Don't throw away your low-calorie sweeteners just because sugar is safer than you thought. Low-calorie sweeteners are "free foods." They make food taste sweet, and have no calories and do not raise blood glucose levels. They do not count as a carbohydrate, a fat, or any other exchange. They can be added to your meal plan instead of substituted.
The Food & Drug Administration (FDA) has approved the use of these low-calorie sweeteners. The American Diabetes Association accepts the FDA's conclusion that these sweeteners are safe and can be part of a healthy diet.
It never occurred to me to do more research.