Keyboard should be fine
At work I've got a Microsoft split keyboard(but not the USB version) and am running W2K. I downloaded an updated driver from Microsoft to enable the extra keys. I find some of the keys useful, the media controls for WinAMP and the calculator button.
Darrell Spice, Jr.
[link|http://home.houston.rr.com/spiceware/|SpiceWare] - We don't do Windows, it's too much of a chore