RH: We support what is on our supported list.
WxPython: We TOLD you, you just need to replace lib x with lib y and it should work fine.
RH: If you replace lib x with lib y, then all the software we tested and support will no longer be supported. While it may work, don't bother calling us if it doesn't.
I've run into this situation several times. It is FAR easier (in my case) to get dispensation to run a Debian box for my projects than force our RH boxes to run them. The general rule is if it needs any vendor support it goes on the RH. If it doesn't, we try to place it on RH but we can then fall back.