A file cabinet cataloged by an Access database that has the registration keys in it and the location of each software and who checked it out last. The IS Secretary (we keep losing them, they either get moved to the Helpdesk or they quit for a better job) takes care of it and monitors who has what software. CDs do have legs and can walk out of the office, never to be seen again.
Who takes them? I have no idea. Must be the King of the PATATO-People! :)