The merging of Python and C seems fairly well thought out. Making strings first-class objects should attract a lot of programmers who grew up on C.
I'm intrigued by the decision of omitting semi-colons. There will be a vast class of programmers who will find that difficult... (think about the polarisation about semi-colon insertion in JavaScript).
The collapsing of all looping into a single statement, for, is daring. And switch has had a significant overhaul.
Wade.