Jimmy Doolittle's [link|http://www.wpafb.af.mil/museum/history/wwii/dtr.htm|Tokyo raid] (come-uppance for Pearl -- we could strike back) was a one-way affair. Sixteen B-25s were launched from 800 miles out (from carriers, no less) to bomb Tokyo. That was 400 miles further out than initially planned, and the Chinese landing sites weren't attainable for most of the crews, many of whom bailed out or ditched their birds. It was a token raid, but to great psychological (and strategic) effect.
The one plane, one bomb, nature of the Hiroshima and Nagasaki raids was significant, and plays into the survivors recollections. Many heard the plane but dismissed it without a thought -- what damage could one plane do? By contrast, the [link|http://tvtokyo.com/Burning.html|Tokyo firebombing] involved 300 aircraft.
[Edit: comeuppance for Perl has yet to be extracted.]