Some top Republican Senators are on the point of mutiny - Warner e.g. This is very much bad news for the Republicans. Remember they used to fight tooth and nail and it hampered their overall presence. There were distinct camps of them and they hated each other - Rockefeller vs. Goldwater.
I think the wheels are about to come off for them. The Ryan decision will make people think - if it's that bad in the justice system, how bad is it everywhere else? (About time.)