At one point in my tech career I did a little inventory of my former close-co-workers. A substantial majority were former as a result of serious mental health issues.

I currently have a roommate who is upset that the people stalking her (a large and complicated conspiracy) are not paying her enough attention. One of those people is a cop in another country, who refused to answer his phone when she called at 4:00 AM. "But it's two hours ahead (or maybe behind, I forgot) there".