Had a Vista Home Premium machine in for disinfect today.
Of course I needed Internet connect to do this, and the Linksys router I'm testing on my network was set with DHCP disabled - So I entered a static IP, Mask, Gateway and DNS. All worked fine and I got the machine cleaned up.
Then I updated it to Vista SP2 . . . no Internet. Went into network config - Default Gateway was blank. Set to DHCP, then back to Static and re-entered all the parameters. Internt worked.
Rebooted. No Internet. No Gateway.
Turns out SP2 deletes the DefaultGateway key from the registry. You have to hand enter a new DefaultGateway key into the registry for your network card.
Good job, Microsoft!