When I worked at a restaurant in college, we had 5000w microwaves. As qualitatively different in how you use them as between a gas stove and a "normal" microwave. Anyway, we once found a roach -- only the once, really! -- and decided to see if we could make it pop.
Put it in the mini-nuke for 10 seconds. It just wandered around inside. (Now keep in mind, this thing would boil 8 oz. of water from room temp in less than 20 seconds.) Tried it for 20 seconds. Nothing. "Screw this ... " Two minutes. It just crawled around. Apparently (I discussed this with a biology major later.) many bugs don't have enough water in their body for microwave to work. All their mass is actual stuff, not just hollow cells full of water.
(PS: We sterilized the inside of the nuke after the experiment.)