It's obvious that the guy who did both Dexter's lab and PP Girls was stylistically influenced by Japanese cartoons. The large eyes and pointed chins are one example. Some others are the Speed Racer nod when Dexter raced down the mountain ahead of the volcano as well as the episode where Dexter is a foreign exchange student in Japan and accidentally wakes up a monster in a volcano while showing off his 'mechs' with some of the local students. Bubbles also likes reading Japanese comic books

Unfortunatly Samuri Jack comes on when I'm not around to watch; shame because it looked really interesting