Python 2.x or 3.x?

wxPython is close to being released for Python 3.x ("Phoenix"), but there may be some other important libraries that still aren't on Python 3.x yet. More - http://wiki.wxpython.org/ProjectPhoenix

Dive into Python 3: http://www.diveinto.org/python3/

HTH a little. Have fun.

Cheers,
Scott.