I wanted to temporarily install AVG Antivirus to run a root kit scan. Turned off his McAfee and shut down SpySweeper.
AVG would not install. Complained it could not update the registry key .../Windows NT/Windows. Checked it with Regedit and sure enough - "You don't have pemission". Well, I could get in and with a couple tries at adding "Administrators" to the blank permissions box it'd free up and show all the normal permissions and let me in. If I exited regedit and tried to install AVG it would be locked again.
Found that if I stayed in regedit and held the Windows key open with it, AVG would install just fine. Same thing on uninstall.