Things were expensive back in those days.
Remember that CPUs and RAM were expensive early on.
Blame it on the 4004 and the 650x. [link|http://www.cpushack.net/CPU/cpu1.html|Linky]:
The 650x was little endian (lower address byte could be added to an index register while higher byte was fetched) and had a completely different instruction set from the big endian 6800. Apple designer Steve Wozniak described it as the first chip you could get for less than a hundred dollars (actually a quarter of the 6800 price) - it became the CPU of choice for many early home computers (8 bit Commodore and Atari products).
Unlike the 8080 and its kind, the 6502 (and 6800) had very few registers. It was an 8 bit processor, with 16 bit address bus. Inside was one 8 bit data register, two 8 bit index registers, and an 8 bit stack pointer (stack was preset from address 256 ($100 hex) to 511 ($1FF)). It used these index and stack registers effectively, with more addressing modes, including a fast zero-page mode that accessed memory addresses from address 0 to 255 ($FF) with an 8-bit address that speeded operations (it didn't have to fetch a second byte for the address).
Back when the 6502 was introduced, RAM was actually faster than microprocessors, so it made sense to optimize for RAM access rather than increase the number of registers on a chip. It also had a lower gate count (and cost) than its competitors.
I don't know the details, but the choice of endian-ness probably had to do with the desire to keep the transistor count down and thus the price.
Cheers,
Scott.
